We have located links that may give you full text access.
[Basement membrane-derived matricryptins as a new target molecule for heart failure treatment].
Extracellular matrix (ECM) is a complex of non-cellular macromolecules which is indispensable not only for maintaining tissue structure but also for regulating the functions of surrounding cells via cell-ECM interaction. Recently, a number of ECM fragments termed "matricryptins" have been identified as novel endogenous bioactive substances, which usually have different bioactivity from that of original ECM. Because most matricryptins derived from basement membrane have anti-angiogenic and anti-tumor effects, they have been initially studied for developing anti-tumor agents. Meanwhile, there are several reports indicating that the expression of basement membrane-derived matricryptins changes in the heart tissue from experimental animal models as well as in the circulating blood from patients with cardiac diseases. Thus, it is logical to hypothesize that the basement membrane-derived matricryptins play roles in the development of cardiac diseases. In this article, we would like to introduce current findings on the functions of matricryptins including ours and discuss the possibility that they serve as a novel target for the treatment of heart failure.
Full text links
Related Resources
Trending Papers
Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.Journal of Personalized Medicine 2024 Februrary 4
Molecular Targets of Novel Therapeutics for Diabetic Kidney Disease: A New Era of Nephroprotection.International Journal of Molecular Sciences 2024 April 4
Perioperative echocardiographic strain analysis: what anesthesiologists should know.Canadian Journal of Anaesthesia 2024 April 11
The 'Ten Commandments' for the 2023 European Society of Cardiology guidelines for the management of endocarditis.European Heart Journal 2024 April 18
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app