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Journal Article
Research Support, Non-U.S. Gov't
Divergent Synthesis of Oxindolylidene Acetates and Spirooxindolopyrrolidones from Arynes.
Organic Letters 2018 March 17
A novel process for the preparation of various ( E)-oxindolylidene acetates using arynes and carbamoylpropiolates has been developed. The utility of this protocol is also further extended to the one-pot synthesis of complex spirooxindolopyrrolidones. This method provides a milder and transition-metal-free access to both of the target scaffolds in moderate to good yields.
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