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PhI(OAc) 2 -mediated dearomative C-N coupling: facile construction of the spiro[indoline-3,2'-pyrrolidine] skeleton.
Organic & Biomolecular Chemistry 2018 March 29
A facile construction of the spiro[indole-3,2'-pyrrolidine] skeleton, through diacetoxyiodobenzene (PIDA) mediated C-N bond-forming dearomatization of C3 sulfonamide linked indole derivatives, has been developed. A variety of spiro-indolepyrrolidines were obtained in moderate to excellent yields under mild conditions.
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