Phosphorus doped graphitic carbon nitride nanosheets as fluorescence probe for the detection of baicalein.

Phosphorus doped graphitic carbon nitride (P-g-C3 N4 ) nanosheets were synthesized by calcination. P-g-C3 N4 nanosheets were characterized by XRD, XPS, TEM, fluorescence, ultraviolet-visible absorption and Fourier transform infrared spectroscopy. The fluorescence of the P-g-C3 N4 nanosheets was gradually quenched with the increase in the concentration of baicalein at room temperature. The proposed probe was used for the determination of baicalein in the concentration 2.0-30μM with a detection limit of 53nM. The quenching mechanism was discussed. The P-g-C3 N4 nanosheets have been successfully applied for effective and selective detection of baicalein in human urine samples and blood samples.