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Research Support, N.I.H., Extramural
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Screening Drugs for Kidney Disease: Targeting the Podocyte.

Joshua S Bryer, Katalin Susztak
Cell Chemical Biology 2018 Februrary 16
Podocytes cover the kidney glomerular basement membrane and present the final barrier in the renal filtration system. Podocyte loss, observed in most kidney diseases, correlates with kidney function decline. In this issue of Cell Chemical Biology, Seiber et al. (2018), using a high-throughput chemical screen, identified the compound CDG-0876, which improved podocyte survival.

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