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Journal Article
Research Support, N.I.H., Extramural
Review
'Big bang' of B-cell development revealed.
Genes & Development 2018 January 16
Earlier studies have identified transcription factors that specify B-cell fate, but the underlying mechanisms remain to be revealed. Two new studies by Miyai and colleagues (pp. 112-126) and Li and colleagues (pp. 96-111) in this issue of Genes & Development provide new and unprecedented insights into the genetic and epigenetic mechanisms that establish B-cell identity.
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