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Management of neurosyphilis: time for a new approach?

Olivia C Smibert, Adam W J Jenney, Denis W Spelman
Internal Medicine Journal 2018 Februrary
Given the long term sequelae of untreated neurosyphilis and insensitive tests to detect treponemes in the cerebrospinal fluid, questions regarding the utility of a lumbar puncture and cerebrospinal fluid analysis either to confirm or exclude neurosyphilis are raised.

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