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Association between epicardial fat volume and fractional flow reserve: An analysis of the determination of fractional flow reserve (DeFACTO) study.
Clinical Imaging 2018 September
BACKGROUND: This study examines the relationship between epicardial fat volume (EFV) and lesion-specific ischemia by fractional flow reserve (FFR).
METHODS: In a study of 173 patients (63.0 ± 8.3 years) undergoing FFR, EFV was determined using cardiac computed tomography. Relationships between EFV and FFR were assessed using multivariable linear and logistic regression.
RESULTS: Using multivariable linear and logistic regression, no association between EFV and FFR was observed (β [SE] = -0.001 [0.003], P = 0.6, OR [95% CI]: 1.02 [0.94-1.11], P = 0.64, respectively).
CONCLUSION: In patients with suspected or known coronary artery disease undergoing invasive angiography, EFV was not associated with FFR.
METHODS: In a study of 173 patients (63.0 ± 8.3 years) undergoing FFR, EFV was determined using cardiac computed tomography. Relationships between EFV and FFR were assessed using multivariable linear and logistic regression.
RESULTS: Using multivariable linear and logistic regression, no association between EFV and FFR was observed (β [SE] = -0.001 [0.003], P = 0.6, OR [95% CI]: 1.02 [0.94-1.11], P = 0.64, respectively).
CONCLUSION: In patients with suspected or known coronary artery disease undergoing invasive angiography, EFV was not associated with FFR.
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