Disseminated Eczema Following Radiotherapy: A Case Report.

BACKGROUND: Radiotherapy-induced acute skin reactions are common and an expected effect of radiotherapy. Eczematous eruptions, however, are rarely reported, with disseminated eczema in particular being infrequently seen and likely underrecognized.

OBJECTIVE: We present a unique case of disseminated vesicular eczema following radiotherapy for ductal carcinoma in situ.

CONCLUSIONS: The development of a localized vesicular eruption with subsequent dissemination can occur following radiotherapy. The mechanism of autosensitization is poorly understood but likely involves a cell-mediated immune response. Recognition is important to prevent excessive and inappropriate investigation and treatment.