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Natural products and ring-closing metathesis: synthesis of sterically congested olefins.

C Lecourt, S Dhambri, L Allievi, Y Sanogo, N Zeghbib, R Ben Othman, M-I Lannou, G Sorin, J Ardisson
Natural Product Reports 2018 January 19
Covering: 2002 to August 2017.This review highlights recent RCM reactions towards the synthesis of sterically congested natural products. It offers an insight into various synthetic targets and approaches and provides information on the evolution of catalysts as powerful tools enabling the use of increasingly challenging diene precursors.

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