We have located links that may give you full text access.
Assessment of pain score and specimen adequacy for ultrasound-guided fine-needle aspiration biopsy of thyroid nodules.
Objective: The aim of this study was to evaluate pain scores and specimen adequacy for ultrasound-guided fine-needle aspiration biopsy (US-FNAB) of thyroid nodules without and with local anesthesia (LA).
Materials and methods: The US-FNAB procedure was performed on 183 patients with and without LA. One puncture was made for solid nodules, and if patients could tolerate it, a two-puncture technique was used for nodules with a cystic change. Four-point verbal rating scores were assessed by a nursing assistant after completion of US-FNAB. To be an adequate specimen, at least six groups of follicular cells are required, and each group should contain at least 10 cells.
Results: Immediately after US-FNAB, 92% of patients with LA and 80% without LA reported no or mild pain ( p =0.01). Most patients tolerated the procedure well, with no pain (82.5%) reported 5 minutes after the procedure. In univariate logistic regression, irregular boundary (odds ratio [OR]: 2.52, 95% confidence interval [CI]: 1.04-6.06, p =0.04), calcification (OR: 2.86, 95% CI: 1.06-7.76, p =0.04), and LA (OR: 0.35, 95% CI: 0.15-0.86, p =0.02) were significantly associated with immediate moderate or severe pain. Specimen adequacy was significantly associated with age (OR: 0.95, 95% CI: 0.92-0.97, p <0.01), heterogeneous echo-texture (OR: 1.76, 95% CI: 1.23-5.17, p =0.01), predominate solid architecture (OR: 2.78, 95% CI: 1.42-5.41, p <0.01), and the use of LA (OR: 3.34, 95% CI: 1.70-6.56, p <0.01). In multivariate logistic regression, patients receiving LA had lower risk of moderate or severe pain (OR: 0.25, 95% CI: 0.09-0.67, p =0.01) and higher chances of specimen adequacy (OR: 4.84, 95% CI: 2.17-10.7, p <0.01) compared to patients who did not receive LA.
Conclusion: US-FNAB is a safe procedure, and most patients report no pain 5 minutes after the procedure. The use of LA was associated with lower immediate pain scales and higher specimen adequacy.
Materials and methods: The US-FNAB procedure was performed on 183 patients with and without LA. One puncture was made for solid nodules, and if patients could tolerate it, a two-puncture technique was used for nodules with a cystic change. Four-point verbal rating scores were assessed by a nursing assistant after completion of US-FNAB. To be an adequate specimen, at least six groups of follicular cells are required, and each group should contain at least 10 cells.
Results: Immediately after US-FNAB, 92% of patients with LA and 80% without LA reported no or mild pain ( p =0.01). Most patients tolerated the procedure well, with no pain (82.5%) reported 5 minutes after the procedure. In univariate logistic regression, irregular boundary (odds ratio [OR]: 2.52, 95% confidence interval [CI]: 1.04-6.06, p =0.04), calcification (OR: 2.86, 95% CI: 1.06-7.76, p =0.04), and LA (OR: 0.35, 95% CI: 0.15-0.86, p =0.02) were significantly associated with immediate moderate or severe pain. Specimen adequacy was significantly associated with age (OR: 0.95, 95% CI: 0.92-0.97, p <0.01), heterogeneous echo-texture (OR: 1.76, 95% CI: 1.23-5.17, p =0.01), predominate solid architecture (OR: 2.78, 95% CI: 1.42-5.41, p <0.01), and the use of LA (OR: 3.34, 95% CI: 1.70-6.56, p <0.01). In multivariate logistic regression, patients receiving LA had lower risk of moderate or severe pain (OR: 0.25, 95% CI: 0.09-0.67, p =0.01) and higher chances of specimen adequacy (OR: 4.84, 95% CI: 2.17-10.7, p <0.01) compared to patients who did not receive LA.
Conclusion: US-FNAB is a safe procedure, and most patients report no pain 5 minutes after the procedure. The use of LA was associated with lower immediate pain scales and higher specimen adequacy.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices 
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app