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Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
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Gasdermin D Flashes an Exit Signal for IL-1.

Teneema Kuriakose, Thirumala-Devi Kanneganti
Immunity 2018 January 17
The IL-1 family of cytokines follows an unconventional pathway of secretion mostly associated with inflammatory cell death. In this issue of Immunity, (Evavold et al., 2017) report gasdermin D pores as channels for active IL-1 release in live phagocytic cells.

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