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JOURNAL ARTICLE
REVIEW
Role of micro-RNAs in breast cancer surgery.
British Journal of Surgery 2018 January
BACKGROUND: The management of breast cancer has changed dramatically in the molecular era. Micro-RNAs can contribute to multiple facets of cancer surgery.
METHODS: This narrative review, based on years of research on the role of micro-RNAs, focused on the potential of these small, robust RNAs to influence all aspects of breast cancer surgery.
RESULTS: Micro-RNAs have a potential role as biomarkers in the diagnosis, prognosis and evaluation of response to therapy in breast cancer. They may also contribute to future therapeutic strategies.
CONCLUSION: The molecular era has changed understanding of cancer. Micro-RNAs have the potential for use in personalized cancer strategies.
METHODS: This narrative review, based on years of research on the role of micro-RNAs, focused on the potential of these small, robust RNAs to influence all aspects of breast cancer surgery.
RESULTS: Micro-RNAs have a potential role as biomarkers in the diagnosis, prognosis and evaluation of response to therapy in breast cancer. They may also contribute to future therapeutic strategies.
CONCLUSION: The molecular era has changed understanding of cancer. Micro-RNAs have the potential for use in personalized cancer strategies.
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