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A well-defined unimolecular channel facilitates chloride transport.
Chemical Communications : Chem Comm 2018 January 32
A unimolecular ion channel was optimized by functionalization with a new type of rigid-rod oligomer. The macrocycle pendant endows chloride selectivity and the fluorescence feature and suitable length of the rod facilitates the visual insertion of channels into the lipid bilayer, resulting in efficient ion transport with an EC50 value of 0.36 μM.
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