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A novel cyclohexenone from Trachyspermum roxburghianum.

A novel cyclohexenone, roxydienone (1), together with 13 known compounds (2-14), were isolated from the seeds of Trachyspermum roxburghianum. The structures of these compounds were established on the basis of their 1D and 2D NMR spectroscopic data. Compounds 1, 2, 7-9 and 14 showed cytotoxicity against NCI-H187 cell line while compounds 1 and 9 showed cytotoxicity against KB cell line. In addition, only compound 13 showed cytotoxicity against MCF-7 cell line.

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