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A mild method for synthesizing carboxylic acids by oxidation of aldoximes using hypervalent iodine reagents.
Organic & Biomolecular Chemistry 2018 January 25
A mild oxidation method for the conversion of aldoximes to carboxylic acids was developed mediated by hypervalent iodine reagents. This method covers a wide range of functionalized aldoximes and proceeds under mild conditions, utilizing PhI(OH)OTs as an oxidant.
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