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Oral Fluoroquinolone Administration and Interacting Substances: The Pediatric Diet Dilemma.
Journal of the Pediatric Infectious Diseases Society 2019 March 29
Concomitant administration of enteral fluoroquinolones (FQs) with divalent or trivalent cation-containing compounds results in a reduction in FQ bioavailability. A review of enteral FQ administration with regards to the timing of divalent or trivalent cation-containing compounds in pediatric patients revealed a high number of inappropriately administered FQs. Suggestions for reducing the number of inappropriately timed FQ administrations are presented here.
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