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Think About the Environment: Cellular Reprogramming by the Extracellular Matrix.

Cell Stem Cell 2018 January 5
In this issue of Cell Stem Cell, Yui et al. (2018) show how tissue regeneration is driven by changes in the microenvironment. During intestinal regeneration, the epithelium is reprogrammed into a fetal state by an altered extracellular matrix (ECM), which is dependent on YAP/TAZ activation.

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