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Non-natural amino acid peptide microarrays to discover Ebola virus glycoprotein ligands.
Chemical Communications : Chem Comm 2018 Februrary 7
We demonstrate a platform to screen a virus pseudotyped with Ebola virus glycoprotein (GP) against a library of peptides that contain non-natural amino acids to develop GP affinity ligands. This system could be used for rapid development of peptide-based antivirals for other emerging or neglected tropical infectious diseases.
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