Effects of Computerized Guideline-Oriented Clinical Decision Support System on Glycemic Control in Diabetic Patients: A Systematic Review and Meta-Analysis.

In a meta-analysis of 4 trials, computerized guideline-oriented clinical decision support system (CDSS) for healthcare providers showed a similar change in glycated hemoglobin (HbA<inf>1C</inf>) from baseline to follow up (weighted mean difference (95% confidence interval (CI)): -0.29 (-0.74, 0.16), p = 0.212), but a reduced proportion of patients with HbA<inf>1C</inf> ≥ 7.0% at follow up (odds ratio (95%CI)): 0.85 (0.74, 0.97), p = 0.014) compared with the control group, suggesting the need for the development of multifaceted computerized CDSS.