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Diarylheptanoids from the fresh pericarps of Juglans sigillata.

Jingjing Liang, Xiaogang Peng, Jia Zhou, Ming Zhou, Hanli Ruan
Natural Product Research 2018 October
One new diarylheptanoid (3S)-3', 4″-epoxy-1-(4'-hydroxylphenyl)-7-(3″-hydroxylphenyl) heptane-3-hydroxy (1), together with eleven known ones (2-12), was isolated from the fresh pericarps of Juglans sigillata. Their structures were elucidated on the basis of extensive spectroscopic methods, including HR-ESI-MS, 1D and 2D-NMR. All isolates were evaluated for their cytotoxic activities in vitro against the growth of human cancer cells lines HT-29 and MCF-7 by MTT assay.

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