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Case Reports
Journal Article
Lung adenocarcinoma and pulmonary metastases coexist in a patient with papillary thyroid carcinoma: A case report.
Medicine (Baltimore) 2017 December
RATIONALE: Multiple primary malignant tumors (MPMTs) are defined as 2 or more independent primary malignancies of different histologies/origins in the same individual. Although the incidence of MPMTs is being increasing, second primary cancer (SPC) is still rare and difficult to distinguish from metastasis. Here, we present a case of thyroid carcinoma with lung metastasis and primary lung cancer.
PATIENTS CONCERNS: The patient was a 66-year-old man diagnosed of papillary thyroid carcinoma (PTC) with lymph nodes, lung, and skeletons metastases. One of the pulmonary nodules had contrary manifestations, such as, noniodine avid, high uptake of F-fluorodexyglucose (F-FDG) and progress after iodine-131 radioiodine therapy.
INTERVENTIONS: CT guided biopsy and I-125 seed brachytherapy of nodule in right upper lobe were performed.
DIAGNOSIS: The patient was diagnosed of PTC with lymph nodes, lung, and skeletons metastases, accompanied by primary lung adenocarcinoma.
OUTCOMES: After 2 years of follow-up, nodules of inferior lobes almost disappeared and the nodule of right upper lobe shrank to only 0.7 cm.
LESSONS: Physicians should be aware of SPC in clinical work, and improve the early diagnosis rate with a variety of examination methods and select the best treatment to improve the prognosis of patients.
PATIENTS CONCERNS: The patient was a 66-year-old man diagnosed of papillary thyroid carcinoma (PTC) with lymph nodes, lung, and skeletons metastases. One of the pulmonary nodules had contrary manifestations, such as, noniodine avid, high uptake of F-fluorodexyglucose (F-FDG) and progress after iodine-131 radioiodine therapy.
INTERVENTIONS: CT guided biopsy and I-125 seed brachytherapy of nodule in right upper lobe were performed.
DIAGNOSIS: The patient was diagnosed of PTC with lymph nodes, lung, and skeletons metastases, accompanied by primary lung adenocarcinoma.
OUTCOMES: After 2 years of follow-up, nodules of inferior lobes almost disappeared and the nodule of right upper lobe shrank to only 0.7 cm.
LESSONS: Physicians should be aware of SPC in clinical work, and improve the early diagnosis rate with a variety of examination methods and select the best treatment to improve the prognosis of patients.
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