[Research progress of Bixie].

The extract of ginkgo leaves showed positive effects on treatments of many diseases, and has been used clinically worldwide. Considering the fact that flavonoids are the main bioactive components in the extract of ginkgo leaves, it is very important to investigate the flavonoid biosynthesis in ginkgo leaves. In this paper, we first reviewed the research progress of flavonoid biosynthesis in different plants, and introduced the flavonoid biosynthesis related genes discovered in ginkgo. Then, several cases of ginkgo researches using high throughput sequencing technology were described in detail. In addition, as an important research area in ginkgo, the changes of flavonoid content and the expression of corresponding genes were discussed. Specifically, our latest results were described. At last, we prospected the development of research area in flavonoid biosynthesis in ginkgo.