Add like
Add dislike
Add to saved papers

Ace Gene Plays A Key Role In Reducing Blood Pressure In Hypertensive Elderlies After Resistance Training Resistance Exercise And Ace Polymorphism.

Hypertension is a difficult disease to control and exercise training plays a key role in hypertension control. Some individuals are not responsive to exercise training, so we highlight the polymorphism of angiotensin I converting enzyme, as a factor responsible for this lack of responsiveness. The aim of this study was to evaluate the influence of ACE (I/D) genotypes on effects of resistance training on blood pressure and chronic inflammation. Eighty-six hypertensive volunteers, aged between 60 and 80, were evaluated. They performed 16 weeks of resistance training at 50% of 1 maximal repetition. The greatest benefits were seen on homozygous of the Insertion allele, whom presented reduction of systolic blood pressure (SBP: 129.31±13.34 vs. 122.56±9.68 mmHg, p<0.001) and diastolic blood pressure (DBP: 79.18±8.05 vs. 70.12±7.71 mmHg, p<0.01) during daytime period, and in 24h period (SBP: 127.12±13.65 vs. 121.06±9.68 mmHg, p<0.001 and DBP: 71.87±8.39 vs. 68.75±8.72 mmHg, p<0.05) and also increased circulating adiponectin levels (4.04±1.79 vs. 6.00±2.81 ng/mL, p<0.01). Other genotypes showed no changes in blood pressure and biochemical parameters. Our results suggest a cardio protective factor of I allele, since only those homozygous showed reductions in blood pressure and increases in adiponectin.

Full text links

We have located links that may give you full text access.
Can't access the paper?
Try logging in through your university/institutional subscription. For a smoother one-click institutional access experience, please use our mobile app.

For the best experience, use the Read mobile app

Mobile app image

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app

All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

By using this service, you agree to our terms of use and privacy policy.

Your Privacy Choices Toggle icon

You can now claim free CME credits for this literature searchClaim now

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app