Evaluation of anterior chamber parameters with spectral-domain optical coherence tomography.

PURPOSE: To evaluate several anterior chamber parameters in healthy young adults using spectral-domain optical coherence tomography and to describe the repeatability and reproducibility of this method.

STUDY DESIGN: Prospective clinical study.

METHODS: Fifty-two eyes of 52 healthy volunteers were enrolled. Manual measurements of the anterior chamber angle (ACA500 and ACA750 ), angle opening distance (AOD500 and AOD750 ), angle-to-angle distance (ATA), anterior chamber width (ACW), and lens vault (LV) were obtained.

RESULTS: The mean nasal ACA500 was 44.87 ± 12.92°; ACA750 , 43.94 ± 10.41°; AOD500 , 672.54 ± 270.19 µm; AOD750, 881.87 ± 290.55 µm. The mean temporal ACA500 was 41.46 ± 11.20°; ACA750 , 41.27 ± 11.31°; AOD500 , 603.15 ± 232.28 µm; AOD750, 823.46 ± 308.76 µm. The differences between the corresponding nasal and temporal parameters were statistically significant. The ACW was 11.97 ± 0.42 mm, the ATA was 12.10 ± 0.43 mm, and the LV was 3.71 ± 232.93 µm. The ACA was highly associated with the LV. The intraclass correlation coefficients ranged from 0.984 to 0.999 for the intraobserver repeatability and from 0.966 to 0.998 for the interobserver reproducibility.

CONCLUSIONS: This study assessed anterior chamber parameters in healthy young adults using spectral-domain optical coherence tomography. This technique reveals the spatial relationships of the ocular structures, provides high-resolution images, and results in high degrees of intraobserver and interobserver repeatabilities.