We have located links that may give you full text access.
Journal Article
Review
An insight into the role of cyclooxygenase and lipooxygenase pathway in renal ischemia.
European Review for Medical and Pharmacological Sciences 2017 November
OBJECTIVE: Renal ischemia (RI) is a clinical condition that occurs due to marked decrease in renal blood flow. The pathophysiology of RI is interlinked with atherosclerotic renal artery stenosis, infarction, organ transplantation and sepsis. The mechanism of RI injury depends on various factors such as inflammatory response, oxidative stress and apoptosis. In this review, we evaluate the role of cyclooxygenase and lipoxygenase in modulating the process of ischemic renal injury.
MATERIALS AND METHODS: This is a literature review of articles published on PubMed and Web of Science in English.
RESULTS: RI is characterized by an inflammatory response and oxidative stress, which are further worsened by the metabolites of the arachidonic acid pathway.
CONCLUSIONS: RI results from a vigorous process involving inflammation and some mediators in a multifaceted interaction. Indulgence of oxidative stress and lipid peroxidation seems to be major factors which promote the inflammation process during RI.
MATERIALS AND METHODS: This is a literature review of articles published on PubMed and Web of Science in English.
RESULTS: RI is characterized by an inflammatory response and oxidative stress, which are further worsened by the metabolites of the arachidonic acid pathway.
CONCLUSIONS: RI results from a vigorous process involving inflammation and some mediators in a multifaceted interaction. Indulgence of oxidative stress and lipid peroxidation seems to be major factors which promote the inflammation process during RI.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app