New soft tissue filler derived from autologous keratin and fibroblast for neck wrinkles.

OBJECTIVE: To assess the effectiveness of injection of autologous keratin gel and fibroblast for neck aging as soft tissue filler.

MATERIALS AND METHODS: Totally 30 volunteers received treatment of autologous keratin and fibroblast for neck wrinkles and 5 of them received hyaluronic acid (HA) treatment as control. Clinical features of the volunteers were collected at 1st, 3rd, 6th, 12th, and 24th months after treatment. The volunteers were independently assessed using Lemperle's methods at different time points.

RESULTS: The neck wrinkles ameliorated observably and no severe complications were reported after treatment. The effect and maintain time of autologous keratin and fibroblast were better than HA control.

CONCLUSION: Autologous keratin and fibroblast as soft tissue filler is an effective treatment option for neck rejuvenation with long-term efficacy for reversing of skin aging.