We have located links that may give you full text access.
English Abstract
Journal Article
[A Preliminary Analysis of Bifidobacterial Species Dependent Influence on the Health of the Elderly].
Sichuan da Xue Xue Bao. Yi Xue Ban = Journal of Sichuan University. Medical Science Edition 2017 September
OBJECTIVE: To analyze the species dependent effect of bifidobacteria to the heath of the middle and elderly.
METHODS: Total 148 healthy volunteers living in Chengdu with 5074 years old were recruited in 2015. The blood samples were collected from them and analyzed physiologically and immunologically. The fecal bifidobacterial were also analyzed by realtime fluorescence quantitative PCR (qPCR) using 16S rRNA targeting designed gene and species specific primers.
RESULTS: Bifidobacterium can be detected in feces of the elderly,the detection rate was 100%,10⁸/g fecal. Especially,more species predominated in the infants were found the tested subjects. Bifidobacterium was positively associated with urea nitrogen ( r=0.214, P<0.05). B. adolescentis was negatively associated with body mass index (BMI) ( r=-0.311, P<0.05),while B.catenulatum was positive to BMI ( r=0.167, P<0.05). B.breve and high density lipoproteincholesterol (HDLC) were negatively correlated ( r=-0.247, P<0.05). Bifidobacterium infantis and HDLC were positively correlated ( r=0.350, P<0.05). Among tested immune parameters,only B.bifidum was found to be positive associated with IgA ( r=0.365, P<0.05).
CONCLUSION: Bifidobacterium might affect the host physiologically and immunology in the species dependent manner. Keeping intestinal bifidobacteria in the ideal species composition might be one of effective ways to slow immune senescence,and promote the health of the elderly.
METHODS: Total 148 healthy volunteers living in Chengdu with 5074 years old were recruited in 2015. The blood samples were collected from them and analyzed physiologically and immunologically. The fecal bifidobacterial were also analyzed by realtime fluorescence quantitative PCR (qPCR) using 16S rRNA targeting designed gene and species specific primers.
RESULTS: Bifidobacterium can be detected in feces of the elderly,the detection rate was 100%,10⁸/g fecal. Especially,more species predominated in the infants were found the tested subjects. Bifidobacterium was positively associated with urea nitrogen ( r=0.214, P<0.05). B. adolescentis was negatively associated with body mass index (BMI) ( r=-0.311, P<0.05),while B.catenulatum was positive to BMI ( r=0.167, P<0.05). B.breve and high density lipoproteincholesterol (HDLC) were negatively correlated ( r=-0.247, P<0.05). Bifidobacterium infantis and HDLC were positively correlated ( r=0.350, P<0.05). Among tested immune parameters,only B.bifidum was found to be positive associated with IgA ( r=0.365, P<0.05).
CONCLUSION: Bifidobacterium might affect the host physiologically and immunology in the species dependent manner. Keeping intestinal bifidobacteria in the ideal species composition might be one of effective ways to slow immune senescence,and promote the health of the elderly.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app