Lensless imaging through multiple phase patterns illumination.

A stable optical system is required to acquire a high-quality image. A motionless lensless setup is designated to obtain high-resolution and large field of view images. The sample is sequentially illuminated with multiple random phase patterns, and the recorded images are subtracted from the system calibration images correspondingly. The resultant images are propagated to the sample plane. The summation of all images yields a final image with resolution of ∼4  μm, field of view of ∼15  mm2, and better signal-to-noise ratio. This technique provides a compact, stable, and cost-effective optical system.