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Water-soluble and UV traceable isatoic anhydride-based reagents for bioconjugation.
Organic & Biomolecular Chemistry 2017 November 23
Isatoic anhydride is elaborated to water soluble bioconjugation reagents that gives functionality and water solubility in one self-cleaning step. This new platform offers high atom economy with carbon dioxide being the only byproduct, and is shown to very quickly and efficiently label proteins in bicarbonate buffered solutions.
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