We have located links that may give you full text access.
LIVER FUNCTION DISORDERS IN PATIENTS WITH FIRST DIAGNOSED PULMONARY TUBERCULOSIS.
Georgian Medical News 2017 October
The patients with pulmonary tuberculosis suffer from hepatic dysfunction due to both hepatotoxic affection with anti-TB drugs and other factors (hypoxia, antioxidant deficiency, intoxication). Therefore, the aim of the research was to study the markers of cytolytic and cholestatic syndromes in cases of hepatic dysfunction in the first diagnosed patients with pulmonary tuberculosis before treatment and in two months of treatment with first-line antituberculous drugs. Three groups of persons were examined: the first group of almost healthy donors (control) - 31 persons. Also, 62 patients were examined for the first time diagnosed pulmonary tuberculosis before treatment and in two months of therapy with first-line antituberculous drugs, which were divided into two groups: the second - the patients (31 persons), who had a moderate intoxication syndrome; the third - the patients (31 persons), who had a severe toxicity syndrome when admitted to hospital. A significant hepatic dysfunction in the first diagnosed patients with pulmonary tuberculosis and severe intoxication syndrome has been established. In the patients with moderate intoxication syndrome, the markers of cytolysis and cholestasis were within normal range before treatment, but after the intensive phase of treatment, the levels of LDH, LF, and GGT were significantly increased. In patients with severe intoxication syndrome, even before treatment, the increase in markers of cytolysis and cholestasis was evidenced. After the intensive phase of treatment, the increase in these rates sustained. It is recommended for patients with pulmonary tuberculosis and severe intoxication syndrome to perform diagnostics of such hepatic dysfunction markers as LDH, ALP and GGT, and if any disorders revealed, to prescribe additional hepatoprotective therapy.
Full text links
Related Resources
Trending Papers
Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.Journal of Personalized Medicine 2024 Februrary 4
Molecular Targets of Novel Therapeutics for Diabetic Kidney Disease: A New Era of Nephroprotection.International Journal of Molecular Sciences 2024 April 4
The 'Ten Commandments' for the 2023 European Society of Cardiology guidelines for the management of endocarditis.European Heart Journal 2024 April 18
A Guide to the Use of Vasopressors and Inotropes for Patients in Shock.Journal of Intensive Care Medicine 2024 April 14
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app