Exploration on the relationship between the elderly osteoporosis and cardiovascular disease risk factors.

OBJECTIVE: To explore and discuss the correlation between osteoporosis and the risk factors of cardiovascular diseases in the elderly.

PATIENTS AND METHODS: A total of 1240 patients, who were hospitalized in our hospital from January 2012 to January 2017, with the age ≥ 65 years old, were selected. All the patients were divided into osteoporosis group and normal bone mass group according to their bone mineral density. The general conditions, biochemical indexes, combined cardiovascular diseases, and the related risk factors, were recorded and analyzed.

RESULTS: The proportion of patients with coronary heart diseases, hyperlipidemia, diabetes mellitus, and smoking in osteoporosis group was significantly higher than that in normal bone mass group (p < 0.05). Results of binary logistic regression analysis showed that homocysteine (HCY), low density lipoprotein (LDL) and total cholesterol (TC) were the major risk factors of osteoporosis in the elderly patients. High-density lipoprotein (HDL) and body weight were protective factors for senile patients with osteoporosis. Female, hypertension, coronary heart diseases, hyperlipidemia, and diabetes mellitus were the main risk factors of complication in the elderly patients with osteoporosis.

CONCLUSIONS: Senile osteoporosis is closely correlated with cardiovascular diseases and related risk factors, including hypertension, coronary heart disease as well as hyperlipidemia, and should be early prevented and treated.