Successful Treatment with 5-fluorouracil and Levofolinate Calcium in Advanced Gastric Cancer Patient with Disseminated Intravascular Coagulation.

Osamu Muto, Masaki Munakata, Kenki Yamagata, Akio Masuda, Kei Kotanagi, Takuya Kichiraku, Rika Satoyoshi, Kazuhiro Kudoh, Toshiya Sawada, Hideaki Miyazawa, Shinichiro Ouchi, Hitoshi Kotanagi, Yuh Sakata

Gan to Kagaku Ryoho. Cancer & Chemotherapy 2017 October

A 32-year-old woman was found to have a gastric adenocarcinoma with multiple bone metastases. Chemotherapy in the first, second and third-line was not effective. Blood examinations showed disseminated intravascular coagulation(DIC)at the end of the second-line chemotherapy. The fourth-line chemotherapy, infusional 5-fluorouracil and levofolinate calcium was performed. This resulted in a good response for DIC. This palliative therapy was effective and safety.

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