We have located links that may give you full text access.
New Approach to Calculation of Renal Cation Clearance in Rats after V1a Receptor Stimulation.
Bulletin of Experimental Biology and Medicine 2017 October
V1a receptor agonist [Phe2 , Ile3 , Orn8 ]-vasopressin produces maximum diuretic and saluretic effects in a dose of 0.1 nmol/100 g body weight: renal excretion of Na+ increases by 50 times in comparison with the initial level over 90 min, excretion of K+ , Mg2+ , and Са2+ increases by 3, 2, and 16 times, respectively. New formulas were proposed for calculation of the clearance considering total cation content in the extracellular fluid and the time of total effect of the injected dose. After injection of V1a receptors agonist, clearance of Na+ was 7% of its total content in the extracellular fluid, the corresponding values for K+ , Mg2+ , and Ca2+ were 63, 35, and 6%, respectively. The proposed approach differs significantly from the standard cation excretion evaluation and characterizes selective shifts in ion balance induced by physiologically active substances and possible side effects due to unbalanced loss of certain ions.
Full text links
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app