[analysis of adherence and compliance to methotrexate therapy in rheumatoid arthritis patients].

Rheumatoid arthritis is chronic inflammatory disease leading to disability and increasing the risk of premature death. Early treatment is crucial for remission and maintaining it for a maximal time. Adherence of the patient to the therapeutic recommendations is necessary. Although this issue is important, its role in achieving of therapeutic success is not fully noted by patients as well as medical stuff. Patients with RA are often non-adherent to rheumatologist's recommendations and non-compliance to the therapy regimen. The causes of this phenomenon are numerous and lie in the patient's attitude to therapy or are patient-independent. To effectively increase the level of adherence and compliance, the detailed medical care, including education of the patient, as well as adaptation of the drug form, by concentrating the active compound, is essential.