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Optical tomographic reconstruction based on multi-slice wave propagation method.

Optics Express 2017 September 19
In optical tomography, it is challenging to obtain high-quality results for complex-structured objects which induce multiple scattering. Nonlinear reconstruction methods outperform linear ones in these situations. A promising nonlinear method is the approach based on beam propagation method, but its accuracy may decrease for complicated structures. In this paper, we describe a novel tomographic reconstruction method using multi-slice wave propagation method (WPM) as the forward model, which simulates the scattering process more precisely but has not been introduced in tomographic reconstruction before. The computational model of WPM is presented. To tackle the computational complexity, we propose an efficient scheme to compute the transmitted field and its derivative. We then use an iterative optimization method to recover the quantitative refraction index distribution. We also discuss the influences of the parameters in the method and how to determine their values. The experimental results demonstrate that this method can address multiple scattering problems and provide high accuracy for complex-structured objects.

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