Relative value of three whole-body MR approaches for PET-MR, including gadofosveset-enhanced MR, in comparison to PET-CT.

Piotr Obara, Andreas Loening, Valentina Taviani, Andrei Iagaru, Brian A Hargreaves, Shreyas Vasanawala

Clinical Imaging 2018 March

PURPOSE: Evaluate MR protocol for PET-MR including coronal DWI (cDWI), fat-suppressed T2 (T2w), and gadofosveset-enhanced T1 (CE).

MATERIALS AND METHODS: 18 patients underwent same-day PET-CT and PET-MR. Image quality and performance of each sequence, and combination of all three sequences, was evaluated with respect to PET-CT.

RESULTS: Lesion conspicuity was best on cDWI, while delineation was best on CE. Considering all three sequences combined, both readers showed good sensitivity and specificity (>80%). Relative sensitivity was highest on CE and lowest on T2w.

CONCLUSIONS: Whole-body MR performed well in detecting malignant lesions compared to PET-CT. CE showed overall highest performance.

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