JOURNAL ARTICLE
RESEARCH SUPPORT, NON-U.S. GOV'T
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Antibiofilm activity of propolis extract on Fusarium species from onychomycosis.

Future Microbiology 2017 November
AIM: The present study evaluated the capacity of three species of Fusarium isolated from onychomycosis to form biofilms and the antibiofilm effect of propolis extract on these biofilms.

MATERIALS & METHODS: The biofilms and antibiofilm effects were evaluated by quantifying the colony-forming units, mitochondrial metabolic activity assays, total biomass by crystal violet staining and scanning electron microscopy.

RESULTS: Propolis extract demonstrated significant antibiofilm efficiency on Fusarium spp. isolates and reduced F. solani, F. oxysporum and F. subglutinans mature biofilms.

CONCLUSION: Propolis extract can be an alternative topical treatment of onychomycosis caused by Fusarium spp.

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