Negative Myoclonus Induced by Ciprofloxacin.

BACKGROUND: Negative myoclonus is characterized by a brief sudden loss of muscle activity, and can be caused by a variety of acquired factors and epilepsy syndromes.

PHENOMENOLOGY SHOWN: We show a clear video example of a patient with an extensive negative myoclonus that was induced by ciprofloxacin.

EDUCATIONAL VALUE: Several neurotoxic effects have been associated with the use of ciprofloxacin, but negative myoclonus has not been reported previously.