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Antioxidant activity of a halogenated monoterpene isolated from a Namibian marine algal Plocamium species.
Journal of Food Science and Technology 2017 September
The antioxidant potential of various marine natural products is well documented. The aim of this study was to evaluate the antioxidant potential of a rare halogenated monoterpene, namely; 1 E ,3 R ,4 S ,5 E ,7 Z -1-bromo-3,4,8-trichloro-7-(dichloromethyl)-3-methylocta-1,5,7-triene ( 1 ) for the first time. This compound was isolated from a Namibian red algal Plocamium species. The antioxidant activity of the compound was evaluated using a series of antioxidant assays, namely; 2,2-diphenyl-1-picryl-hydrazyl radical (DPPH), reducing power, nitric oxide (NO) and hydrogen peroxide (H2 O2 ). The compound demonstrated remarkable DPPH, NO and H2 O2 scavenging activities with IC50 values of 0.05 ± 0.01, 4.18 ± 0.22 and 5.58 ± 1.11 mM, respectively. The reducing power of the compound increased with an increase in concentration. These results were compared to the absorbance of ascorbic acid, which was used as a standard control in all the antioxidant assays. The results strongly suggest that compound 1 is a promising antioxidant agent with potential commercial applications.
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