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JOURNAL ARTICLE
RESEARCH SUPPORT, NON-U.S. GOV'T
CRISPR-RT: a web application for designing CRISPR-C2c2 crRNA with improved target specificity.
Bioinformatics 2018 January 2
Summary: CRISPR-Cas systems have been successfully applied in genome editing. Recently, the CRISPR-C2c2 system has been reported as a tool for RNA editing. Here we describe CRISPR-RT (CRISPR RNA-Targeting), the first web application to help biologists design crRNAs with improved target specificity for the CRISPR-C2c2 system. CRISPR-RT allows users to set up a wide range of parameters, making it highly flexible for current and future research in CRISPR-based RNA editing. CRISPR-RT covers major model organisms and can be easily extended to cover other species. CRISPR-RT will empower researchers in RNA editing.
Availability and implementation: Freely available at https://bioinfolab.miamioh.edu/CRISPR-RT.
Contact: [email protected].
Supplementary information: Supplementary data are available at Bioinformatics online.
Availability and implementation: Freely available at https://bioinfolab.miamioh.edu/CRISPR-RT.
Contact: [email protected].
Supplementary information: Supplementary data are available at Bioinformatics online.
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