The Effect of Short-term Treatment with Fennel on Bone Density in Postmenopausal Women: A Randomized Controlled Trial.

OBJECTIVES: The goal of this study is to assess the effect of fennel on bone density.

METHODS: This was a double-blind, randomized, placebo-controlled trial, which studied sixty eligible postmenopausal women, who were randomly assigned to fennel and placebo groups. Then, the dual energy X-ray absorptiometry was utilized to measure bone mineral density (BMD) and bone mineral content (BMC) of the spine, femoral neck, intertrochanter, and trochanter at the baseline and after three-month follow-up.

RESULTS: The mean BMD and BMC at lumbar spine ( P = 0.14, P = 0.504), total hip femoral ( P = 0.427, P = 0.471), trochanter ( P = 0.075, P = 0.07), intertrochanter, ( P = 0.864, P = 0.932) and femoral neck ( P = 0.439, P = 0.641) was not significantly different between the fennel and placebo groups.

CONCLUSIONS: The results of this study did not approve the effect of fennel on bone density in post-menopausal women. However, to gain deeper insights, further studies with longer durations and larger sample sizes are recommended.