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Peroral infektionsprofylax vid allmän­­kirurgiska ingrepp bör utvärderas mer - Trimetoprim–sulfametoxazol kombinerat med metronidazol tycks fungera vid kolorektal kirurgi – om det ges vid rätt tid.

Läkartidningen 2017 September 23
Orally administered infection prophylaxis in elective colorectal surgery  Orally administered trimethoprim-sulfamethoxazole and metronidazole given at a defined time point at least two hours before elective colorectal surgery can be used as prophylaxis with a small increase in superficial surgical site infections (SSI), if motivated by other benefits such as environmental concerns. However, in upper malignant or bariatric surgery it should be used only in study form. Further, the methods of infection surveillance have a great potential to be improved.

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