Treatment of hepatitisC virus with direct-acting antivirals: Practical aspects and current situation.

HepatitisC virus infection is a significant public health problem. The introduction of direct-acting antiviral agents, whose efficacy is greater than 90% in all patient groups (including those with cirrhosis), has represented a highly relevant change compared with classical interferon-based therapies. Tolerance for these antiviral agents is significantly better, and the treatment duration is shorter. This review updates the treatment of hepatitisC virus infection with the new direct-acting antiviral agents.