We have located links that may give you full text access.
Probing Early Motion Processing With Eye Movements: Differences of Vestibular Migraine, Migraine With and Without Aura in the Attack Free Interval.
Headache 2018 Februrary
BACKGROUND: Migraineurs, in between headache attacks, have a different sensitivity to sensory motion stimuli compared to non-migraineurs.
METHODS: This cross-sectional laboratory study examines the motion processing in migraineurs using ocular following responses (OFR) elicited by large field random dot patterns and open-loop smooth pursuit eye movements (PS) elicited by a single target moving on a homogenous background. Eye movements were recorded with a video-oculographic system (EyeSeeTec® ) and stimuli presented on a CRT at 100 Hz repetition rate to horizontal stimuli of a velocity of 2.5 to 160°/s. Eye movements were analyzed during the open loop period.
RESULTS: We recorded 43 migraine patients: 14 migraine with (MwA), 19 without aura (MwoA), 10 vestibular migraine (VM), and 16 healthy controls. ANOVA analysis of OFR responses amplitudes showed significant differences in the subgroup (control, MwA, MwoA, and VM) (F3,409 =29.8, P < .001), stimulus velocity (F6,406 =12.6, P < .001), and interaction (F18,394 =1.9, P = .015). Fitting the OFR response velocity tuning by a "Weibull" function showed that the subgroups were different in the linear scaling factor (F4,53 = 4.3, P < .001) but not in parameters defining the overall form of the tuning function. In contrast, the initial open-loop responses of PS were not changed compared to control for the three different migraine subgroups.
CONCLUSION: From the findings, we hypothesize that in the migraine subtypes, MwA and VM, there is different sensory motion information processing for OFR compared to MwoA and control, not explained by a neuronal hyperexcitability in V5. OFR might be a possible subclinical marker in the future to diagnose MwA and VM.
METHODS: This cross-sectional laboratory study examines the motion processing in migraineurs using ocular following responses (OFR) elicited by large field random dot patterns and open-loop smooth pursuit eye movements (PS) elicited by a single target moving on a homogenous background. Eye movements were recorded with a video-oculographic system (EyeSeeTec® ) and stimuli presented on a CRT at 100 Hz repetition rate to horizontal stimuli of a velocity of 2.5 to 160°/s. Eye movements were analyzed during the open loop period.
RESULTS: We recorded 43 migraine patients: 14 migraine with (MwA), 19 without aura (MwoA), 10 vestibular migraine (VM), and 16 healthy controls. ANOVA analysis of OFR responses amplitudes showed significant differences in the subgroup (control, MwA, MwoA, and VM) (F3,409 =29.8, P < .001), stimulus velocity (F6,406 =12.6, P < .001), and interaction (F18,394 =1.9, P = .015). Fitting the OFR response velocity tuning by a "Weibull" function showed that the subgroups were different in the linear scaling factor (F4,53 = 4.3, P < .001) but not in parameters defining the overall form of the tuning function. In contrast, the initial open-loop responses of PS were not changed compared to control for the three different migraine subgroups.
CONCLUSION: From the findings, we hypothesize that in the migraine subtypes, MwA and VM, there is different sensory motion information processing for OFR compared to MwoA and control, not explained by a neuronal hyperexcitability in V5. OFR might be a possible subclinical marker in the future to diagnose MwA and VM.
Full text links
Related Resources
Trending Papers
Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.Journal of Personalized Medicine 2024 Februrary 4
Molecular Targets of Novel Therapeutics for Diabetic Kidney Disease: A New Era of Nephroprotection.International Journal of Molecular Sciences 2024 April 4
The 'Ten Commandments' for the 2023 European Society of Cardiology guidelines for the management of endocarditis.European Heart Journal 2024 April 18
A Guide to the Use of Vasopressors and Inotropes for Patients in Shock.Journal of Intensive Care Medicine 2024 April 14
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app