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Dynamic Looping Interactions: Setting the 3D Stage for the Macrophage.
Molecular Cell 2017 September 22
The mechanisms by which 3D chromatin looping interactions mediate cell type-specific gene expression are an active area of investigation. In this issue of Molecular Cell, Phanstiel et al. (2017) annotate five classes of loops during macrophage development and predict candidate factors involved in their regulation.
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