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JOURNAL ARTICLE
RESEARCH SUPPORT, NON-U.S. GOV'T
Copper-Catalyzed Tandem Aerobic Oxidative Cyclization for the Synthesis of Polysubstituted Quinolines via C(sp 3 )/C(sp 2 )-H Bond Functionalization.
Journal of Organic Chemistry 2017 October 7
One-pot Cu-catalyzed tandem aerobic oxidative cyclization for the synthesis of quinolines from 2-vinylanilines/2-arylanilines and 2-methylquinolines via C(sp3 )-H/C(sp2 )-H bond functionalization has been developed. Dioxygen as an ideal oxidant has been employed for this transformation. The substrates bearing various functional groups perform well in this process and generate the desired products in moderate to good yields.
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