Gender differences in brain networks during verbal Sternberg tasks: A simultaneous near-infrared spectroscopy and electro-encephalography study.

Gender differences in psychological processes have been of great interest in a variety of fields including verbal fluency, emotion processing and working memory. Previous studies suggested that women outperform men in verbal working memory (VWM). However, the inherent mechanisms are still unclear. To obtain a deeper insight into the gender differences in brain networks in VWM, this study used near-infrared spectroscopy (NIRS) and electro-encephalography (EEG) simultaneously to investigate gender-related brain networks during verbal Sternberg tasks. NIRS results confirmed that women surpass men in VWM from the perspective of both brain activation and connectivity. Results of EEG (effective connectivity and event-related spectral power) showed that men tend to use a more visuospatial strategy to encode memory. In addition, novel analysis methods of brain networks can provide useful information about the gender specifics of brain functions. Gender-related pseudo-color maps constructed from all channels of average HbO2 activity during low- and high-load tasks (from 0 to 6 seconds after beginning).