We have located links that may give you full text access.
JOURNAL ARTICLE
MULTICENTER STUDY
Establishing age-specific reference intervals for anti-Müllerian hormone in adult Chinese women based on a multicenter population.
AIM OF THIS STUDY: Anti-Müllerian hormone (AMH) is useful for the assessment of ovarian reserve and treatment of individualized in vitro fertilization (IVF). The aim of this study is to establish AMH reference interval for adult Chinese women on the Beckman Beckman DxI 800 platform.
MATERIAL AND METHODS: From May to September 2013, serum from 1169 apparently healthy adult females from five representative cities in China (Beijing, Hangzhou, Guangzhou, Dalian and Urumqi) were collected, and AMH was analyzed on the platform of Beckman DxI 800 automated chemiluminescence immunoassay. Multiple regression analysis was used to investigate the effects of region, sex, age, body mass index (BMI), systolic blood pressure (SBP), exercise on AMH. Age specific reference interval for AMH was established.
RESULTS: The main factor affecting AMH levels was age (B=-0.756, P<0.001). The AMH reference intervals for adult Chinese women aged 19-24years, 25-29years, 30-34years, 35-39years, 40-44years, 45-49years and ≥50years were 0.74-16.06, 0.67-11.64, 0.50-9.99, 0.09-8.33, 0.04-4.09, 0.01-1.46 and <0.01-0.18ng/ml, respectively. The linear, quadratic and cubic models could either provide good fit regression model to describe the decline of AMH with age (R2 =0.40).
CONCLUSION: This study firstly established age-specific reference intervals for AMH in Chinese women based on multicenter population.
MATERIAL AND METHODS: From May to September 2013, serum from 1169 apparently healthy adult females from five representative cities in China (Beijing, Hangzhou, Guangzhou, Dalian and Urumqi) were collected, and AMH was analyzed on the platform of Beckman DxI 800 automated chemiluminescence immunoassay. Multiple regression analysis was used to investigate the effects of region, sex, age, body mass index (BMI), systolic blood pressure (SBP), exercise on AMH. Age specific reference interval for AMH was established.
RESULTS: The main factor affecting AMH levels was age (B=-0.756, P<0.001). The AMH reference intervals for adult Chinese women aged 19-24years, 25-29years, 30-34years, 35-39years, 40-44years, 45-49years and ≥50years were 0.74-16.06, 0.67-11.64, 0.50-9.99, 0.09-8.33, 0.04-4.09, 0.01-1.46 and <0.01-0.18ng/ml, respectively. The linear, quadratic and cubic models could either provide good fit regression model to describe the decline of AMH with age (R2 =0.40).
CONCLUSION: This study firstly established age-specific reference intervals for AMH in Chinese women based on multicenter population.
Full text links
Related Resources
Trending Papers
Proximal versus distal diuretics in congestive heart failure.Nephrology, Dialysis, Transplantation 2024 Februrary 30
World Health Organization and International Consensus Classification of eosinophilic disorders: 2024 update on diagnosis, risk stratification, and management.American Journal of Hematology 2024 March 30
Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment.Clinical Research in Cardiology : Official Journal of the German Cardiac Society 2024 April 12
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app