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JOURNAL ARTICLE
OBSERVATIONAL STUDY
What is the value of neonatal autopsy? Pathological and clinical correlation in 135 cases.
Archivos Argentinos de Pediatría 2017 October 2
INTRODUCTION: Neonatal autopsy is a valuable, critical diagnostic method to provide genetic counseling for future pregnancies.
POPULATION AND METHODS: Retrospective study including all neonatal autopsies performed on deceased neonates at Clínica y Maternidad Suizo Argentina between January 1998 and December 2006. The rate of autopsies was established; the diagnosis indicated in the medical record was compared to autopsy findings.
RESULTS: Out of 227 deceased infants, 135 autopsies were performed (rate: 59.5%). Concordance was complete in 25% of autopsies. New information was found in 26%, which had significant implications for genetic counseling.
CONCLUSIONS: The rate of autopsies was 59.5%. Pathological and clinical correlation and unsuspected findings with implications for genetic counseling demonstrate the relevance of performing neonatal autopsies systematically.
POPULATION AND METHODS: Retrospective study including all neonatal autopsies performed on deceased neonates at Clínica y Maternidad Suizo Argentina between January 1998 and December 2006. The rate of autopsies was established; the diagnosis indicated in the medical record was compared to autopsy findings.
RESULTS: Out of 227 deceased infants, 135 autopsies were performed (rate: 59.5%). Concordance was complete in 25% of autopsies. New information was found in 26%, which had significant implications for genetic counseling.
CONCLUSIONS: The rate of autopsies was 59.5%. Pathological and clinical correlation and unsuspected findings with implications for genetic counseling demonstrate the relevance of performing neonatal autopsies systematically.
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